Life on the road is hard. Here are a few things that make it a little easier.

The Laundress. They make a product called Crease Release that should be in every travelers' arsenal. All you do is simply spray the formula onto wrinkled clothes, and, voila, they become unwrinkled! We seriously buy this stuff by the case. 
They also sell individual packets of gentle liquid detergent in case you need to rinse something out in the sink at your hotel.
Go to thelaundress.com

Votivo scented travel candles. They can turn any musty hotel room or dressing room into a dream. Kim's favorite is red currant.
Go to zandia.com

Miss Oops Sponge. The packaging is extremely 'girly' but the product works like magic on stains. Just rub the dry sponge onto the offended area and it's gone. 
Go to missoops.com

Evian spray. Buy the 2 oz. travel size (put in a ziplock when going through security). Who would think that something so simple would be so refreshing on those long trips. Keeps your skin hydrated on long flights and it feels great!

Lush. They make a wonderful dry soap/ shampoo (airport security friendly) that works great when you just want to take a carry-on bag. They also make the most outrageously decadent bath bombs that I adore.
Go to lush.com

Magellan's. I love this site for everything from adaptors to hand- held baggage scales (takes the guessing out of overweight baggage charges).
Go to magellans.com

We love flowers! Why not send your sweetie some gorgeous flowers from the road or just send them to yourself!

overstock.com is a great resource for roses and orchids for people like myself that prefer to arrange their own flowers. teleflora.com has wonderful, high quality arrangements ready for delivery!